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Bacterial Overgrowth of the Small Intestine (SIBO)

Uncover the Cause of Unexplained Abdominal Symptoms with Breath Testing

SIBO Profiles are non-invasive breath tests which capture exhaled hydrogen (H2) and methane (CH4) gases following patient ingestion of a lactulose solution to evaluate bacterial overgrowth of the small intestine.

When should testing for SIBO be considered?

Symptoms of SIBO are non-specific, encompassing abdominal pain/distention, diarrhea, and flatulence.

Conditions commonly associated with SIBO include:

  • IBS

  • IBD

  • Celiac Disease

  • Diabetes

  • Fibromyalgia

  • Rosacea

  • Parkinson's Disease

  • Obesity


Risk factors for development of SIBO include structural/anatomic issues, motility disorders, organ system dysfunction, elderly age and various medications (recurrent antibiotics, PPIs) that alter the gut microflora populations.

While aspiration of small bowel fluid (followed by culture and bacterial count) is considered to be the current gold standard for diagnosis of SIBO, it is not routinely performed because it requires a complex, invasive technique, and is costly. As a result, experts suggest breath testing for the diagnosis of small intestinal bacterial overgrowth.


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